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Identification Name Tiotropium Accession Number DB01409 Description. Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. 1,2,3,4,5 Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation. 1,2,3,4,5

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Absorption. Losartan is approximately 33% orally bioavailable. 1,3,4 Losartan has a T max of 1 hour and the active metabolite has a T max of 3-4 hours. 1,3,4 Taking losartan with food decreases the C max but does only results in a 10% decrease in the AUC of losartan and its active metabolite. 1,3,4 A 50-80mg oral dose of losartan leads to a C max of 200-250ng/mL. 1

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1,200 mg/day elemental calcium PO is the recommended dietary allowance (RDA). To prevent the development of osteoporosis in postmenopausal women, most reference texts recommend an intake of 1 to 1.5 g/day PO of elemental calcium; the 2006 guidelines of the North American Menopause Society recommend a target intake of 1,200 mg/day of elemental calcium PO in postmenopausal women.

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ACLS Algorithm #5: Suspected Stroke Algorithm. The final ACLS algorithm reviewed here is the suspected stroke algorithm. The suspected stroke algorithm is designed to streamline and simplify the process of early management and care of the patient with ischemic stroke.

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Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias. Its use is only recommended in those with dangerous arrhythmias or when significant symptoms cannot be managed with other treatments. Its use does not decrease a person's risk of death. It is taken by mouth or injection into a vein.

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Formoterol: Long-acting selective beta2-adrenergic agonist with rapid onset of action; acts locally as bronchodilator; stimulates intracellular adenyl cyclase, which results in increased cyclic adenosine monophosphate levels, causing relaxation of bronchial smooth muscle and inhibition of release of mast cell mediators

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Supraventricular tachycardia can be treated with 0.1 mg/kg adenosine IV push to a max of 6 mg. If the first dose is unsuccessful, follow it with 0.2 mg/kg adenosine IV push to a max of 12 mg. If adenosine is unsuccessful, proceed to synchronized cardioversion.

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